发明名称 GLUCOPYRANOSE DERIVATIVE
摘要 PROBLEM TO BE SOLVED: To obtain a compound represented by general formula (I) useful as a prophylactic and/or a therapeutic agents for HIV infectious diseases, asthma, atopic dermatitis, rhinitis, conjunctivitis, allergic bronchopulmonary aspergillosis, allergic eosinophilic gastroenteropathy, nephritis, nephropathy, hepatitis, arthritis, rheumatoid arthritis, rejection of transplanted organs and shock during bacterial infection. SOLUTION: This glucopyranose derivative is represented by the general formula (I) [wherein A is O or CH2; R0 and R1 are each H, OH, a (phenyl- substituted) alkoxy, an alkylthio, a halogen, t-butyldimethylsilyloxy, t- butyldiphenylsilyloxy or OSO3H; R2 and R3 are each a group represented by formula (II), formula (III) or formula (IV); E is OCO or E-R3 is H, OH, a (phenyl- substituted) alkoxy, t-butyldimethylsilyloxy or t-butyldiphenylsilyloxy; and R4 is H, a halogen or CH2-R10] or its salt.
申请公布号 JP2001172250(A) 申请公布日期 2001.06.26
申请号 JP19990353800 申请日期 1999.12.14
申请人 ONO PHARMACEUT CO LTD 发明人 TAKAOKA YOSHIKAZU;SHIBAYAMA SHIRO
分类号 C07H13/04;A61K31/015;A61K31/215;A61K31/35;A61K31/351;A61K31/695;A61K31/7024;A61P1/00;A61P1/16;A61P11/02;A61P11/06;A61P13/12;A61P27/02;A61P29/00;A61P31/18;A61P37/00;C07C305/20;C07D309/10;C07D309/30;C07F9/09;(IPC1-7):C07C305/20 主分类号 C07H13/04
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