发明名称 Method of establishing the optimal radiation dose
摘要 A method for determining the number of millicuries to be administered to a patient so as to deliver a given centigray (cGy) dose to either the patient's lean body or the patient's total body. The method includes the steps of injecting a radioactive tracer into a patient, determining radiation levels in the whole body, calculating a geometric mean based on the radiation levels, determining the percent-injected activity remaining in the body at each time point, plotting the percent-injected activity versus calculated time from infusion on a log-linear graph, determining the effective half live and the rate of clearance from the log-linear graph, cross-indexing the effective half-life value with the patient's body weight, and multiplying the determined amount of therapeutic millicuries per centigray by the amount of desired centigray to be administered.
申请公布号 US6251362(B1) 申请公布日期 2001.06.26
申请号 US19960584646 申请日期 1996.01.11
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 WAHL RICHARD L.;ZASADNY KENNETH R.
分类号 A61N5/00;A61K51/00;A61K51/10;A61N5/10;(IPC1-7):A61K51/00 主分类号 A61N5/00
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