| 摘要 |
Amphiphilic molecules, comprised of a hydrophilic moiety capable of hydrogen bond donation and acceptance and a hydrophobic moiety lacking hydrogen bond donors, aggregate in the molten state and can be extruded into fibres. The aggregates exist as thermodynamically stable glasses at ambient temperature and are slowly degraded in water <i>in vitro</i>, in a predictable manner via hydrogen bond cleavage, to predictable water soluble components. These components may exhibit pharmacological activity. |
