发明名称 |
Halogenated sulphamate-, phosphonate-, thiophosphonate-, sulphonate- and sulphonamide- compounds as inhibitors of steroid sulphatase |
摘要 |
A compound is described. The compound has the formula (Ia) as presented in the FIG. 1; wherein: X is a ring having at least 4 atoms in the ring; K is hydrocarbyl group; Rh1 is an optional halo group; Rh2 is an optional halo group; at least one of Rh1 and Rh2 is present; Rs is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group. The compound is capable of inhibiting steroid sulphatase (STS) activity. |
申请公布号 |
AU2190601(A) |
申请公布日期 |
2001.06.25 |
申请号 |
AU20010021906 |
申请日期 |
2000.12.07 |
申请人 |
STERIX LIMITED |
发明人 |
MICHAEL JOHN REED;BARRY VICTOR LLOYD POTTER;HATEM HEJAZ;ATUL PUROHIT |
分类号 |
A61K31/566;A61P1/02;A61P1/04;A61P1/14;A61P3/10;A61P5/44;A61P7/00;A61P7/02;A61P7/04;A61P9/00;A61P9/04;A61P9/10;A61P11/02;A61P11/06;A61P15/00;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P19/10;A61P21/04;A61P25/00;A61P25/06;A61P25/08;A61P25/18;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;C07J41/00;C12Q1/34 |
主分类号 |
A61K31/566 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|