发明名称 2-phenyl-quinoline derivatives, preparation method and therapeutic use thereof
摘要 Compounds of general formula (I) in which: A represents a hydrogen atom or a hydroxyl, B represents a hydrogen atom or a C1-3 alkyl group, R1 represents a phenyl optionally substituted with a halogen, a hydroxyl, a C1-3 alkoxy, C1-3 alkyl, C1-3 fluoroalkyl or C1-2 perfluoroalkyl group, R2, R3 and R6, which may be identical or different, each represent a hydrogen atom, a halogen, a C1-6 alkyl or C2-6 alkenyl group, R4 and R5, which may be identical or different, each represent a hydrogen atom, a C1-6 alkyl, C2-6 alkenyl or C3-6 cycloalkyl group, or R4 and R5 together form a C2-6 alkylene or C3-6 alkenylene chain to give, with the nitrogen to which they are attached, a heterocycle, this heterocycle optionally being substituted with a C1-4 alkyl group. Therapeutic use.
申请公布号 AU2526001(A) 申请公布日期 2001.06.25
申请号 AU20010025260 申请日期 2000.12.14
申请人 SANOFI-SYNTHELABO 发明人 PHILIPPE R BOVY;ALAIN BRAUN;CHRISTOPHE PHILIPPO
分类号 A61K31/47;A61P1/00;A61P9/14;A61P11/02;A61P13/02;A61P25/06;C07D215/14 主分类号 A61K31/47
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