In one aspect, the present invention concerns the use of certain cyclic quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula (I) wherein n is an integer of from 0 to 4; R1 and E are independently selected from -CH2-R16 and a group represented by formula (II).
申请公布号
WO0144192(A1)
申请公布日期
2001.06.21
申请号
WO2000CA01506
申请日期
2000.12.15
申请人
NORTRAN PHARMACEUTICALS INC.;CHOI, LEWIS, SIU, LEUNG;BEATCH, GREGORY, N.;PAGE, CLIVE, P.
发明人
CHOI, LEWIS, SIU, LEUNG;BEATCH, GREGORY, N.;PAGE, CLIVE, P.