NOVEL POLYPEPTIDE AND DNA THEREOF

摘要

A novel polypeptide having physiological activities relating to anterior pituitary hormones (LT, FSH, TSH, etc.) and the like; a DNA encoding this polypeptide; and a method of screening compounds or salts thereof promoting or inhibiting the activities of the above polypeptide. Because of having physiological activities relating to anterior pituitary hormones (LT, FSH, TSH, etc.) and the like, the above polypeptide is usable as remedies for hypertension, autoimmune diseases, heart failure, etc. This polypeptide is also useful as a reagent in screening compounds or salts thereof promoting or inhibiting the activities of the polypeptide. It is expected that the compounds obtained by the screening are usable as preventives and remedies for hypertension, autoimmune diseases, heart failure, etc. An antibody against this polypeptide, which can recognize specifically this polypeptide, is usable in, for example, quantifying the polypeptide in a liquid specimen.