发明名称 |
USE OF WICKING AGENT TO ELIMINATE WASH STEPS FOR OPTICAL DIFFRACTION-BASED BIOSENSORS |
摘要 |
The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized micropsheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of analyte-specific receptors. Finally, the system includes a wicking agent which permits the system to be a single step system which avoids the necessity of any additional rinsing steps. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image, such as a hologram, is produced which can be easily seen with the eye or optionally, with a sensing device. |
申请公布号 |
WO0144813(A2) |
申请公布日期 |
2001.06.21 |
申请号 |
WO2000US42768 |
申请日期 |
2000.12.12 |
申请人 |
KIMBERLY-CLARK WORLDWIDE, INC. |
发明人 |
KAYLOR, ROSANN, M.;CHOI, ABRAHAM, B.;GRUNZE, MICHAEL, HEINRICH, HERBERT;CHIDEBELU-EZE, CHIBUEZE, OBINNA |
分类号 |
C40B60/14;G01N33/543;(IPC1-7):G01N33/53 |
主分类号 |
C40B60/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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