摘要 |
The present invention provides an inexpensive and sensitive system and metho d for detecting analytes present in a medium. The system comprises a diffracti on enhancing element, such as functionalized micropsheres, which are modified such that they are capable of binding with a target analyte. Additionally, t he system comprises a polymer film, which may include a metal coating, upon whi ch is printed a specific, predetermined pattern of analyte-specific receptors. Finally, the system includes a wicking agent which permits the system to be a single step system which avoids the necessity of any additional rinsing step s. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image, such as a hologram, is produced which can be easily seen with the eye or optionally, with a sensing device. |
申请人 |
KIMBERLY-CLARK WORLDWIDE, INC. |
发明人 |
GRUNZE, MICHAEL HEINRICH HERBERT;CHOI, ABRAHAM B.;CHIDEBELU-EZE, CHIBUEZE OBINNA;KAYLOR, ROSANN M. |