发明名称 Verfahren zur Herstellung kombinatorischer Aminbibliotheken
摘要 The invention relates to a combinatorial library comprised of at least two different amines of general formulas (I) and/or (Ia), wherein; R<1> and R<2> can be the same or different and, independent of one another, represent substituted or non-substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl or trialkylsilyl or R<1> and R<2>, together with the nitrogen atom on which they are bound, can form a substituted or non-substituted cycloalkyl ring which, in addition to the nitrogen atom, can contain yet at least one additional heteroatom that is selected from the group consisting of nitrogen, oxygen or sulfur; R<3> is selected from hydrogen and methyl, which can be optionally substituted with 1-3 fluorine atoms; R<4> and R<5> can be the same or different and, independent of one another, represent substituted or non-substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, or alkynyl; or a salt thereof. The invention also relates to a method for producing combinatorial libraries at least comprising amines of the general formulas.
申请公布号 DE19960377(A1) 申请公布日期 2001.06.21
申请号 DE19991060377 申请日期 1999.12.14
申请人 MERCK PATENT GMBH 发明人 BUCHHOLZ, HERWIG;WELZ-BIERMANN, URS
分类号 B01J21/06;B01J21/10;B01J31/02;B01J31/12;C07B61/00;C07C209/66;C07C211/03;C07C211/08;C07C211/17;C07C211/21;C07C211/35;C07C211/48;C07D295/02;C07D295/023;C07D295/03;C07F7/08;(IPC1-7):C07B61/00 主分类号 B01J21/06
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