METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE CYANOHYDRINS USING R-OXYNITRILASE

摘要

The invention relates to the production of (R)-enantiomeric, optically activ e cyanohydrins by reacting an aldehyde or a ketone with a cyanide group donor in the presence of (R) oxynitrilase, wherein a reaction mixture comprising a) a n aldehyde or a ketone dissolved in an organic solvent; said organic solvent i s immiscible or only slightly miscible with water, b) an aqueous R)-oxynitrila se solution and c) a cyanide group donor is stirred in such away that an emulsi on is formed which remains intact until the end of the enzymatic reaction. Afte r the enzymatic reaction has terminated, the (R)-cyanohydrin is isolated from the reaction mixture.