| 摘要 |
<p>Compounds of general formula (I) are useful in the treatment and prevention of β3-related diseases including diabetes, obesity and hypertention wherein R1 is hydrogen, halogeno, or hydroxyl; R2 is lower alkyl or benzyl; R3 is OR, halogeno, trifluoromethyl, lower alkyl, lower acyl, NR4R4', nitro, or cyano; R is hydrogen, lower alkyl, benzyl, or optionally substituted lower acyl; R?4 and R4'¿ are each independently hydrogen, lower alkyl, lower acyl, benzyl, or -SO¿2R?5; R5 is lower alkyl or benzyl; W is oxygen, a secondary nitrogen atom (NH), or sulfur; and * represents an asymmetric carbon atom.</p> |
