| 摘要 |
A photodynamic therapy (PDT) device (20) utilizes a non-coherent light sourc e (22) to activate a photoreactive agent for treating a diseased site in a patient's eye (10). When activated, the photoreactive agent causes a desired change in the diseased tissue of the treatment site. In one embodiment, the photoreactive agent is preferentially absorbed by the diseased tissue at the treatment site, and the light from the PDT device (20) is directed generally at the site. In another embodiment, the photoreactive agent is less selectively absorbed by the diseased tissue, and the light from the PDT devi ce (20) is focused onto the diseased treatment site. The device preferably focuses the light emitted by a source using totally internally reflective (TIR) lenses (14), convergent lenses (24), divergent lenses, and/or deformab le lenses. One embodiment incorporates a plurality of light sources of differen t wavebands, including a waveband that does not activate the photoreactive agent, so that the light source can be used to precisely target the focal point at the desired treatment site. Once targeted, a light source is energized to produce light in a waveband that activates the photoreactive agent and can penetrate different depths of tissue. The PDT device (20) can be incorporated into a headset or in an ophthalmic slit lamp.
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