发明名称 HYDROXYACETAMIDOBENZENESULPHONAMIDE DERIVATIVES
摘要 A compound of formula (I) wherein: R<1>, R<2>, R<3>, R<4>, R<5>, R<6> and R<7> are as defined within; or a pharmaceutically acceptable salt or an <i>in vivo</i> hydrolysable ester thereof is described. The use of compounds of formula (I) in the production of an elevation of PDH activity in a warm-blooded animal such as a human being are also described. Pharmaceutical compositions, methods and processes for preparation of compounds of formula (I) are detailed.
申请公布号 WO0117955(A3) 申请公布日期 2001.06.21
申请号 WO2000GB03303 申请日期 2000.08.30
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BUTLIN, ROGER, JOHN;PEASE, JANET, ELIZABETH;BLOCK, MICHAEL, HOWARD;NOWAK, THORSTEN;BURROWS, JEREMY, NICHOLAS 发明人 BUTLIN, ROGER, JOHN;PEASE, JANET, ELIZABETH;BLOCK, MICHAEL, HOWARD;NOWAK, THORSTEN;BURROWS, JEREMY, NICHOLAS
分类号 C07D295/22;A61K31/18;A61K31/40;A61K31/44;A61K31/4406;A61K31/445;A61K31/5375;A61P3/10;A61P9/00;A61P9/10;A61P31/04;A61P43/00;C07C311/46;C07C323/67;C07D207/12;C07D211/46;C07D211/96;C07D213/76;C07D295/26;(IPC1-7):C07C311/46;A61P5/48 主分类号 C07D295/22
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