发明名称 METHODS FOR INDUCING T-CELLULAR TOLERANCE FOR TISSUE OR ORGAN TRANSPLA - NT
摘要 <p>transplantation techniques. SUBSTANCE: patient receives (i) allogenic or xenogenic cell, which expresses donor's antigens and which bears ligand on cellular surface intended to interact with receptor on the surface of a recipient cell, the latter mediating contact-dependent helper and effecter function, and (ii) receptor antagonist, which inhibits ligand-receptor interaction, are injected to patient. Thus, tolerance for donor's antigens is induced. EFFECT: enabled successful transplantation of donor tissue or organ with no immuno-mediated rejection of donor's transplant. 38 cl, 13 dwg, 2 tbl, 2 ex</p>
申请公布号 RU2169009(C2) 申请公布日期 2001.06.20
申请号 RU19960122475 申请日期 1995.04.25
申请人 TRASTIZ OF DARTMUT KOLLEDZH;JUNIVERSITI OF MASSACHUSETTS MEDIKAL SENTER 发明人 NOELLE RANDOL'F DZH.;D'JURI FIONA KH.;PARKER DEHVID S.;EHPPEL MAJKL S.;FILIPS NEHNSI E.;MORDES DZHON P.;GRENAJR DEHJL L.;ROSSINI ALDO A.
分类号 C12N15/02;A61K31/00;A61K35/14;A61K35/38;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61P3/00;A61P3/10;A61P37/00;A61P37/06;C07K14/705;C07K16/28;C12P21/08;C12R1/91;(IPC1-7):A61K39/00 主分类号 C12N15/02
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