发明名称 Enzyme-based assay for determining effects of exogenous and endogenous factors on cellular energy production
摘要 Disclosed herein is a method for determining the effect of either endogenous and exogenous factors on the energy producing capacity of cells comprising the steps of obtaining a sample of whole blood from the test subject, in which sample there is present an endogenous source of an oxidoreductase enzyme participating, directly or indirectly, in cellular energy production; adding to a portion of that sample an effective amount of a substrate associated with the enzyme implicated in cellular energy production; and measurement of an analytical signal the level of which is proportional to the endogenous level of an endogenously present cofactor of the enzyme. Preferably, in the method of the invention, the test subject is a mammal. More preferably, the test subject is a human.
申请公布号 US6248552(B1) 申请公布日期 2001.06.19
申请号 US19970957656 申请日期 1997.10.24
申请人 BIRKMAYER PHARMACEUTICALS 发明人 BIRKMAYER GEORG D.
分类号 C12Q1/26;C12Q1/32;(IPC1-7):C12Q1/26 主分类号 C12Q1/26
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