发明名称 |
5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines |
摘要 |
This invention is directed to the use of dihydropyrimidine compounds, which are selective antagonists for cloned human alpha1C receptors, for the treatment of benign prostatic hyperplasia and other diseases where antagonism of the human alpha1C receptor is useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-identified compounds and a pharmaceutically acceptable carrier.
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申请公布号 |
US6248747(B1) |
申请公布日期 |
2001.06.19 |
申请号 |
US19990291553 |
申请日期 |
1999.04.14 |
申请人 |
SYNAPTIC PHARMACEUTICAL CORPORATION |
发明人 |
NAGARATHNAM DHANAPALAN;CHIU GEORGE;DHAR T. G. MURALI;WONG WAI C.;MARZABADI MOHAMMAD R.;GLUCHOWSKI CHARLES |
分类号 |
C07D239/22;A61K;A61K31/505;A61K31/506;A61P3/06;A61P9/06;A61P13/02;A61P13/08;A61P15/00;A61P25/04;A61P43/00;C07D;C07D239/30;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D413/14;C07D453/02;C07D491/04;C07D491/048;C07D521/00;(IPC1-7):A61K31/505;C07D239/32 |
主分类号 |
C07D239/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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