BENZHYDRYLAMINE DERIVATIVES

摘要

Novel benzhydrylamine derivatives represented by general formulas (I) and (II) are useful as reaction reagents for the solid-phase synthesis of polypeptide amides making use of 9-fluorenylmethyloxycarbonyl group ("Fmoc"). An intermediate for these derivatives represented by the general formula (III) is also disclosed: (see formula I) (see formula II) (see formula III) where R1 and R2 each independently represents a C1-3 lower alkyl; n is an integer of 1-4; ~ is 1 or 2; and m is 1 or 2.