| 摘要 |
The invention relates to a local preparation having combined haemostatic and bactericidal effect. The haemostatic preparations comprise, as active haemostatic and bactericidal ingredients, a polyelectrolyte matrix of a polymeric carboxylic acid of a predetermined average molecular weight range and a bactericidal agent, wherein bactericidal agent is silver in the form of dissolved, free silver ions, oligomeric silver clusters, silver colloidal nanoparticles or any combination of such. Methods of production of these haemostatic preparations on the basis of poly(acrylic acid) of a predetermined average molecular weight range by introducing silver salts into the aforementioned polymeric acid, adjusting pH of the solution and irradiation by light, where applicable, are described. The compositions may be liquid or dry. |
