发明名称 |
Contortrostatin (cn) and methods for its use in preventing metastasis and other conditions |
摘要 |
Contortrostatin, a homodimeric disintegrin, modulates the adhesion, motility, and invasiveness of integrin expressing tumor cells. When formulated as a pharmaceutically acceptable composition, the proteins can be used to treat patients by inhibiting or disrupting disease processes associated with an integrin binding to an alpha nu beta 3 or alpha nu beta 5 integrin. |
申请公布号 |
AU2077001(A) |
申请公布日期 |
2001.06.18 |
申请号 |
AU20010020770 |
申请日期 |
2000.12.09 |
申请人 |
THE UNIVERSITY OF SOUTHERN CALIFORNIA |
发明人 |
FRANCIS S. MARKLAND JR.;QING ZHOU |
分类号 |
C12N5/06;A61K38/00;A61K38/17;A61P7/02;A61P9/10;A61P17/02;A61P19/10;A61P35/04;A61P43/00;C07K14/47 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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