发明名称 |
Modulation of in vivo glutamine and glycine levels in the treatment of autism |
摘要 |
A method of treating autism in a patient. The method includes administering to the patient an effective amount of a glutamine level reducing agent, a glycine level reducing agent or combinations thereof. Representative glutamine level reducing agents are phenylbutyrate and phenylacetate, and a representative glycine level reducing agent is sodium benzoate. Optionally, an N-methyl-D-aspartate receptor antagonist can also be administered to the patient. A representative N-methyl-D-aspartate receptor antagonist is dextromethorphan. |
申请公布号 |
AU4517201(A) |
申请公布日期 |
2001.06.18 |
申请号 |
AU20010045172 |
申请日期 |
2000.12.05 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
JOHN, A. PHILLIPS;SUSAN G. MCGREW |
分类号 |
A61K31/19;A61K31/192;A61K31/485 |
主分类号 |
A61K31/19 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|