发明名称 METHOD FOR THE PREVENTION AND/OR TREATMENT OF ATHEROSCLEROSIS
摘要 The instant invention provides a method for raising serum HDL cholesterol levels comprising administering a therapeutically effective amount of an LXR ligand to a patient in need of such treatment. It further provides a method for using an LXR ligand to stimulate expression of the ABC1 gene. LXR ligands can be used for preventing and treating atherosclerosis and related conditions.
申请公布号 WO0141704(A2) 申请公布日期 2001.06.14
申请号 WO2000US33098 申请日期 2000.12.07
申请人 MERCK & CO., INC.;SPARROW, CARL, P.;ONDEYKA, JOHN, G.;SINGH, SHEO, BUX 发明人 SPARROW, CARL, P.;ONDEYKA, JOHN, G.;SINGH, SHEO, BUX
分类号 A61K45/00;A61K31/222;A61K38/17;A61K48/00;A61P9/10;A61P15/10;A61P25/28;A61P43/00;C07C69/16;(IPC1-7):A61K/ 主分类号 A61K45/00
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