| 摘要 |
<p>The invention provides methods and materials for detecting supracolonic aerodigestive premalignant and malignant neoplasms. Specifically, the invention provides methods and materials for determining whether a stool sample from a mammal contains a neoplasm-specific marker from a neoplasm located in the supracolonic aerodigestive tissue of a mammal. These neoplasm-specific markers are selected from the group consisting of nucleic acids having a point mutation (K-ras, APC, p53), nucleic acids that reflect microsatellite instability (BAT-26), and high integrity nucleic acids (DNA longer than 200 bp).</p> |
