发明名称 REAGENT AND METHOD FOR DELIVERY OF MOLECULES INTO CELLS
摘要 Disclosed is a carrier peptide and a conjugate comprising a carrier peptide and a target molecule and a method for delivery of the target molecule into a cell. The carrier peptide contains from 10-15 amino acids, having a core sequence of 3-5 hydrophobic amino acids flanked by flanking amino acid sequences. The core sequence comprises residues selected from proline and leucine such that there is at least one each of proline and leucine and is symmetrical about an amino acid or a bond. Also disclosed is a method for delivery of a target molecule into a cell and a method for measuring a cellular process.
申请公布号 WO0141811(A2) 申请公布日期 2001.06.14
申请号 WO2000GB04593 申请日期 2000.12.04
申请人 AMERSHAM PHARMACIA BIOTECH UK LIMITED;HORTON, JEFFREY, KENNETH;SMITH, JOHN, ANTHONY;TEEAR, MICHELLE, LEIGH;KENDALL, JONATHAN, MARK;MICHAEL, NIGEL, PAUL 发明人 HORTON, JEFFREY, KENNETH;SMITH, JOHN, ANTHONY;TEEAR, MICHELLE, LEIGH;KENDALL, JONATHAN, MARK;MICHAEL, NIGEL, PAUL
分类号 A61K47/48;A61K49/00;C07K7/08;(IPC1-7):A61K47/48 主分类号 A61K47/48
代理机构 代理人
主权项
地址