发明名称 |
HERPES SIMPLEX VIRUS FOR TREATING UNWANTED HYPERPROLIFERATIVE CELL GROWTH |
摘要 |
The present invention relates to pharmaceutical compositions, kits, and methods of use thereof, comprising, a mutant human herpes simplex-type 1 virus, which is cytopathic to susceptible hyperproliferative cells, such as neoplastic cells. Preferably, the virus does not produce a fully functionally active wild-type ICP0 polypeptide coded for the IE gene 1.
|
申请公布号 |
WO0141801(A2) |
申请公布日期 |
2001.06.14 |
申请号 |
WO2000US33355 |
申请日期 |
2000.12.08 |
申请人 |
ONYX PHARMACEUTICALS, INC. |
发明人 |
LAQUERRE, SYLVIE;HERMISTON, TERRY |
分类号 |
C12Q1/02;A61K35/76;A61K45/00;A61P1/00;A61P35/00;C07K14/035;C12N7/04;(IPC1-7):A61K39/12 |
主分类号 |
C12Q1/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|