| 发明名称 |
APOPTOSIS INHIBITORY POLYPEPTIDE, GENE AND POLYNUCLEOTIDE ENCODING IT AND COMPOSITIONS CONTAINING THE SAME |
| 摘要 |
At least one serine residue in the amino acid sequence of wild type Bc1-2 protein is substituted by alanine or aspartic acid to give a polypeptide having a potentiated apoptosis inhibitory activity compared with the wild type Bc1-2 protein.
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| 申请公布号 |
WO0142459(A1) |
申请公布日期 |
2001.06.14 |
| 申请号 |
WO2000JP08667 |
申请日期 |
2000.12.07 |
| 申请人 |
HISAMITSU PHARMACEUTICAL CO., INC.;SHIBAZAKI, FUTOSHI;KUMA, HIDEKAZU |
发明人 |
SHIBAZAKI, FUTOSHI;KUMA, HIDEKAZU |
| 分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K48/00;A61P1/16;A61P9/10;A61P21/04;A61P25/00;A61P25/28;A61P27/02;A61P43/00;C07K14/47;C12N7/00;C12N15/12;C12N15/18;(IPC1-7):C12N15/12;C07K14/82;A61K38/17 |
主分类号 |
C12N15/09 |
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