| 摘要 |
The present invention relates to devices and methods of modifying the neuron al activity of a neural system comprising neurons, comprising, one or more of t he following steps, measuring the neuronal activity of a neural system; and applying an oriented electric field to said neural system effective to modif y the neuronal activity of the neural system, wherein the magnitude and polari ty of said applied electric field is changed in response to the measured neuron al activity. The present invention also relates to devices and methods for treating brain disorders, such as epilepsy and Parkinson's disease, comprising, one or more of the following steps, applying a sub-threshold and oriented electric field in situ to the brain of a patient having such a disorder in an amount effective to reduce the abnormal activity of the brain , wherein the electric field is applied through field electrodes in contact wi th the brain.
|
