| 摘要 |
The present invention provides immunogens for generating anti-neonicotinoid antibodies as well as antibodies, methods, reagents, and kits for determinin g the presence of one or more neonicotinoid insecticides in a sample by immunoassay. The present invention has particular application to determinati on of the concentration of neonicotinoid insecticides applied to a plant propagation materials such as seed, said antibody is selective for a compoun d of formula (I) wherein A is 2-chloropyrid-5-yl or 2-chlorothiazol-5-yl; R an d R3 independently are hydrogen or C1-C4alkyl; R1 and R2 independently are hydrogen or C1-C4alkyl or R1 and R2 are taken together with the nitrogen ato ms to which they are attached to form an imidazoline or an oxadiazine ring; and X is N-NO2 or N-CN. Also claimed is a compound of formula (IA) and protein conjugate of formula (II) in which PR is a protein residue of a carrier molecule selected from the group consisting of a purified protein derivative (PPD, Tuberculin) from Diptheria virus, bovine serum albumin, cationized bovine serum albumin, human serum albumin, ovalbumin and keyhole limpet hemocyanin; or an enzyme residue selected from the group consisting of alkaline phosphatase, horseradish peroxidase, and .beta.-galactosidase.</SDO AB>
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