发明名称 |
4-PYRIDINYL-N-ACYL-L-PHENYLALANINES |
摘要 |
Compounds of Formula (I) are disclosed wherein R1-R7 are as defined in the application and which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4 and, therefore, are useful for treating diseases whose symptoms and or damage are related to the binding of VCAM-1 to cells expressing VLA-4, such as chronic inflammatory diseases.
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申请公布号 |
CA2392566(A1) |
申请公布日期 |
2001.06.14 |
申请号 |
CA20002392566 |
申请日期 |
2000.11.29 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
TILLEY, JEFFERSON WRIGHT;SIDDURI, ACHYUTHARAO;KAPLAN, GERALD LEWIS |
分类号 |
A61K31/4418;A61K31/7135;A61P1/00;A61P11/06;A61P19/02;A61P25/00;A61P29/00;A61P43/00;C07D213/64;(IPC1-7):C07D213/64 |
主分类号 |
A61K31/4418 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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