发明名称 |
NOVEL METHODS FOR THE TREATMENT AND PREVENTION OF ILEUS |
摘要 |
Novel methods for the treatment and/or prevention of ileus. The methods may comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods inclu de piperidine-N-alkylcarboxylates, quaternary morphinans, opium alkaloid derivatives and quaternary benzomorphans. The methods are particularly suitable for treating and/or preventing postsurgical ileus and postpartum ileus.
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申请公布号 |
CA2393141(A1) |
申请公布日期 |
2001.06.14 |
申请号 |
CA20002393141 |
申请日期 |
2000.11.29 |
申请人 |
ADOLOR CORPORATION |
发明人 |
FARRAR, JOHN J.;CARPENTER, RANDALL L.;SCHMIDT, WILLIAM K.;SCHIED, PETER J. |
分类号 |
C07D221/26;A61K31/00;A61K31/439;A61K31/445;A61K31/451;A61K31/473;A61K31/485;A61K45/00;A61P1/00;A61P43/00;C07D211/22;C07D489/00;C07D489/02;(IPC1-7):A61K31/451;A61K31/452;A61K31/454;A61K31/474 |
主分类号 |
C07D221/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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