发明名称 |
METHODS FOR CARBON-CENTERED RADICAL MEDIATED HEAVY HYDROGEN LABELING OF COMPOUNDS |
摘要 |
The solvent accessible reduced carbon atoms in a molecule of interest are labeled with heavy hydrogen. The carbon atoms are labeled under anaerobic, aqueous conditions by exposing the molecule of interest to a hydrogen atom abstractor in the presence of a heavy hydrogen source and a heavy hydrogen donor. If the hydrogen atom abstractor is hydroxyl radical, an electron scavenger source is provided. Optionally, an internal reference is provided to facilitate experimental reproducibility.
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申请公布号 |
WO0073325(A8) |
申请公布日期 |
2001.06.14 |
申请号 |
WO2000US15169 |
申请日期 |
2000.06.01 |
申请人 |
ANDERSON, VERNON, E.;GOSHE, MICHAEL, B. |
发明人 |
ANDERSON, VERNON, E.;GOSHE, MICHAEL, B. |
分类号 |
C07K1/13;(IPC1-7):C07K1/13 |
主分类号 |
C07K1/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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