NOVEL METHODS FOR THE TREATMENT AND PREVENTION OF DIZZINESS AND PRURITUS

摘要

Novel methods for the treatment and/or prevention of dizziness and/or pruritus. The methods may comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods include piperidine-N-alkylcarboxylates, quaternary morphinans, opium alkaloid derivatives and quaternary benzomorphans. The methods are particularly suitable for treating and/or preventing dizziness and/or pruritus associated with opioid compounds.