| 发明名称 |
INDUCTION OF PROGRAMMED CELL DEATH BY N5 GENE |
| 摘要 |
The present invention concerns methods and compositions for treating cancer in a subject. These methods and compositions utilize the activities associated with the N5 gene product, p84N5. p84N5 contains a functional death domain, can interact with the retinoblastoma gene product and is normally localized to the nucleus of cells. Increasing the activity level of p84N5 in cancer cells is beneficial for the treatment of cancer.
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| 申请公布号 |
WO0116168(A3) |
申请公布日期 |
2001.06.14 |
| 申请号 |
WO2000US24075 |
申请日期 |
2000.08.31 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
GOODRICH, DAVID;DOOSTZADEH, JALEH;YIN, SHENMIN |
| 分类号 |
A61K38/00;A61K48/00;C07K14/47;(IPC1-7):C07K14/47;C12N15/12;C12N5/10;C12N15/86;C12N15/861;C12N15/869;C12N15/867 |
主分类号 |
A61K38/00 |
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