Mittel und Verfahren zur Diagnose von Lyme Borreliose sowie Borreliose-Impfstoff

摘要

The invention relates to agents for diagnosing and/or treating Lyme disease which contain the antigens of glyceraldehyde-3-phosphate-dehydrogenase (GAPDH), oligopeptide permease, oligopeptide ABC transporter periplasmic BP(oppA-2)(Bb), glycosyl transferase IgtD homologue, heat shock protein 90, VLSE fragment, (U76406) putative v1s rec. cassette V1s6 Borrelia burgdorferii, flagellin protein Borrelia garinii, (AE001578) conserved hypothetical protein cp32-6 Borrelia burgdorferii, membrane assoc. protein p66 precursor Borrelia burgdorferii, oligopeptide ABC transporter periplasmic BP (oppA-4)(Bc), fructose-biphosphate aldose (fba) Borrelia burgdorferii, DNAK Protein Heat Shock Protein 70 Borrelia burgdorferii, orfE Borrelia burgdorferii, outer surface protein B precursor Borrelia burgdorferii, L-lactate dehydrogenase (ldh), P83/100 gene Borrelia burgdorferii, enolase 2-phosphoglycerate Borrelia burgdorferii, flagellin protein Borrelia garinii, hypothetical protein BBE28 Borrelia burgdorferii, DNA direct. RNA polymerase (rpoA) homologue, P66 protein (fragment), flagellin (fragment), DNA direct. RNA polymerase, integral outer membrane protein p66, pyruvate kinase (pyk) homologue; phosphoglycerate kinase (pgk) and/or BBU28760 NID and/or fragments thereof and/or the nucleic acid sequences encoding said antigens and/or said fragments.