5-MEMBERED RING COMPOUNDS

摘要

5-Membered ring compounds represented by general formula (I), optically active isomers thereof or salts of the same. These compounds have physiological activities including a carcinostatic effect. In said formula the bond shown by the dotted line in the 5-membered ring represents that this 5-membered ring may be either a cyclopentene ring having a double bond or a saturated cyclopentane ring, and when the 5-membered ring is a cyclopentene ring, X is OR1, Y is =O and Z is H, and when it is a cyclopentane ring, X is =O, Y is OR2 and Z is OR3, (wherein R1 is R4 or -(CO)-R5; R2 is H, -R6 or -(CO)-R7; and R3 is H, R8 or (CO)-R9 (wherein R4, R5, R6, R7, R8 and R9 are the same or different and each represents an aliphatic, aromatic or aliphatic aromatic group, and R5, R7 and R9 may be each H), provided that the case where R2=R3=H is excluded); and W represents a residue obtained by eliminating SH from an SH-containing compound.