| 发明名称 |
Human papilloma virus vaccine with disassembled and reassembled virus-like particles |
| 摘要 |
Human Papillomavirus vaccine formulations which contain virus-like particles (VLPs) can be made more stable and have an enhanced shelf-life, by treating the VLPs to a disassembly and reassembly process. Also provided are formulation buffers to long term stable storage of VLPs.
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| 申请公布号 |
US6245568(B1) |
申请公布日期 |
2001.06.12 |
| 申请号 |
US20000524624 |
申请日期 |
2000.03.13 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
VOLKIN DAVID B.;MACH HENRYK;SHI LI |
| 分类号 |
A61K9/08;A61K39/12;A61K47/02;A61K47/14;A61K47/16;A61K47/34;A61P31/12;(IPC1-7):G01N31/00 |
主分类号 |
A61K9/08 |
| 代理机构 |
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