发明名称 Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific T-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide
摘要 The present invention is relative to nucleic acids containing at least one nucleic acid sequence coding for a recombinant polypeptide, which recombinant polypeptide contains at least partially the primary sequence of the invariant chain and at least one primary sequence from a specific T-cell epitope and is processed in a desired manner in antigen-presenting cells for binding the specific T-cell epitope to MHC II molecules.
申请公布号 US6245904(B1) 申请公布日期 2001.06.12
申请号 US19980043293 申请日期 1998.03.16
申请人 THE UNIVERSITY OF TUBINGEN 发明人 MELMS ARTHUR;MALCHEREK GEORG
分类号 A61K38/00;A61K48/00;C07K14/33;C07K14/725;C07K14/74;C12N1/21;C12N15/12;(IPC1-7):C07H21/04;C12N1/20;C12N15/00;C12N5/06;A01N43/04 主分类号 A61K38/00
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