发明名称 |
Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific T-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide |
摘要 |
The present invention is relative to nucleic acids containing at least one nucleic acid sequence coding for a recombinant polypeptide, which recombinant polypeptide contains at least partially the primary sequence of the invariant chain and at least one primary sequence from a specific T-cell epitope and is processed in a desired manner in antigen-presenting cells for binding the specific T-cell epitope to MHC II molecules.
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申请公布号 |
US6245904(B1) |
申请公布日期 |
2001.06.12 |
申请号 |
US19980043293 |
申请日期 |
1998.03.16 |
申请人 |
THE UNIVERSITY OF TUBINGEN |
发明人 |
MELMS ARTHUR;MALCHEREK GEORG |
分类号 |
A61K38/00;A61K48/00;C07K14/33;C07K14/725;C07K14/74;C12N1/21;C12N15/12;(IPC1-7):C07H21/04;C12N1/20;C12N15/00;C12N5/06;A01N43/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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