发明名称 Selectively binding ultrasound contrast agents
摘要 The invention discloses an ultrasound contrast media comprising a microbubble shell and a composition of the general formula:wherein A is an ultrasound contrast agent microbubble-shell binding moiety; P is a spacer arm; and L is a ligand. The present invention discloses compositions, methods of imaging, and methods for attachment of targeting ligands to USCM agents, allowing selective targeting of USCM agents to desired sites.
申请公布号 US6245318(B1) 申请公布日期 2001.06.12
申请号 US19970863647 申请日期 1997.05.27
申请人 MALLINCKRODT INC. 发明人 KLIBANOV ALEXANDER L.;LYLE LEON R.;THOMAS M. ELIZABETH
分类号 A61K49/00;A61K49/22;(IPC1-7):A61B8/00 主分类号 A61K49/00
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