Peptide antigens

摘要

IgE-blocking agents and methods of their use have been developed for desensitizing an individual to an antigen. These IgE-blocking agents work by blocking the antigen-binding site of the IgE molecules and thereby preventing the antigen from binding. These agents typically have up to one IgE binding site present per molecule so as prevent any cross-linking of IgE which could lead to an allergic reaction. Methods of using these novel IgE blocking agents include administering the agents to alleviate or prevent allergic reactions as well as administering the agents to decrease the risk of allergic reactions during immunotherapy or "rush" immunotherapy. Compositions and kits comprising these IgE binding agents are also provided.