TETRAHYDROPYRIDINE- OR 4-HYDROXYPIPERIDINEALKYLAZOLES OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF

摘要

organic chemistry, pharmacy. SUBSTANCE: invention relates to novel tetrahydropyridine- or 4-hydroxypiperidinealkylazoles of the formula (I) where R1,R2,R3 and R6 means hydrogen, halogen atom, C1-C6-alkyl, C1-C6-perfluoroalkyl, C1-C6-alkoxyl, or two adjacent radicals can form benzene ring condensed with the parent compound; A means carbon atom and dotted line means additional bond, or A means carbon atom bound with hydroxyl group (C-OH) and dotted line means the absence of additional bond; n = 2-6; Z1,Z2,Z3 mean nitrogen atom or substituted carbon atom, or their physiologically acceptable salts showing antipsychotic or anxiolytic activity. EFFECT: new compounds indicated above, improved methods of synthesis, valuable medicinal properties. 10 cl, 3 tbl, 9 ex