发明名称 |
ANALOGE NUKLEOSIDE, WIE ANTIVIRALE EINSCHLIESSLICH INHIBITOREN DER RETROVIRALEN REVERSTRANSKRIPTASE UND DER DNA POLYMERASE DES HEPATITIS B VIRUS |
摘要 |
A compound of the formula I <CHEM> wherein: nuc is the residue of a nucleoside analogue bonded through its single hydroxy group on the cyclic or acyclic saccharide moiety, R1 is hydroxy, amino or carboxy; optionally having esterified/amide bonded thereon a C4-C22 saturated or unsaturated, optionally substituted fatty acid or alcohol, or an aliphatic L-amino acid; R2 is the residue of an aliphatic L-amino acid; L1 is a trifunctional linker group; L2 is absent or a difunctional linker group; and pharmaceutically acceptable salts thereof. <IMAGE> |
申请公布号 |
DE69800753(D1) |
申请公布日期 |
2001.06.07 |
申请号 |
DE1998600753 |
申请日期 |
1998.08.14 |
申请人 |
MEDIVIR AB, HUDDINGE |
发明人 |
ZHOU, XIAO-XIONG;JOHANSSON, NILS-GUNNAR;WAEHLING, HORST |
分类号 |
C07D473/18;A61K31/52;A61K31/522;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61K31/708;A61P31/12;A61P31/16;A61P31/18;A61P43/00;C07B61/00;C07D213/80;C07D213/85;C07D307/68;C07D473/00;C07D473/32;C07D473/34;C07D513/04;C07H17/08;C07H19/04;C07H19/16;C07H19/173 |
主分类号 |
C07D473/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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