发明名称 CHIMERIC FLAVIVIRUS VACCINES
摘要 <p>A chimeric live, infectious, attenuated virus containing a yellow fever virus, in which the nucleotide sequence for a prM-E protein is either deleted, truncated, or mutated, so that functional prM-E protein is not expressed, and integrated into the genome of the yellow fever virus, a nucleotide sequence encoding a prM-E protein of a second, different flavivirus, so that the prM-E protein of the second flavivirus is expressed.</p>
申请公布号 WO0139802(A1) 申请公布日期 2001.06.07
申请号 WO2000US32821 申请日期 2000.12.01
申请人 ORAVAX, INC. 发明人 CHAMBERS, THOMAS, J.;MONATH, THOMAS, P.;GUIRAKHOO, FARSHAD
分类号 A61K39/12;A61K39/193;A61K48/00;A61P31/12;C07K14/18;C12N7/01;C12N7/04;(IPC1-7):A61K39/12 主分类号 A61K39/12
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