| 摘要 |
<p>The present invention relates to arrays of discrete sensing elements of glycans (glycoarrays) wherein glycans are immobilized on a solid support (glycochips). Furthermore, the present invention relates to a method of producing such glycoarrays comprising immobilization of a glycan on a preferably streptaviding coated sensing surface via biotin or a derivative thereof. In addition, the present invention relates to the use of such glycoarrays for discriminating complex biological samples, diagnosing a disease which correlates with the presence or absence of glycan binding molecules as well as to methods of identifying an organism by generation of signal pattern from a biological sample, which is indicative for the presence or absence of a particular organism. Furthermore, the present invention relates to a kit comprising the glycoarray of the invention useful in diagnostic assays.</p> |
