发明名称 |
A NOVEL AND PRACTICAL SEROLOGICAL ASSAY FOR THE CLINICAL DIAGNOSIS OF LEISHMANIASIS |
摘要 |
Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa <i>Leishmania</i> is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detection of antibodies to <i>Leishmania</i> parasite soluble antigens and antigen-capture ELISAs for the detection of <i>Leishmania</i> parasite soluble antigens in host samples. Also disclosed are immunodiagnostic kits for the detection of <i>Leishmania</i> parasite circulating antigens or IgM and IgG antibodies in a sample from subject having visceral, cutaneous or canine leishmaniasis. In these methods and kits, detection may be done photometricall y or visually. The methods and kits also allow the visualization of <i>Leishmania</i> amastigotes or promastigotes in a sample.
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申请公布号 |
WO0140755(A2) |
申请公布日期 |
2001.06.07 |
申请号 |
WO2000US32523 |
申请日期 |
2000.11.30 |
申请人 |
U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND |
发明人 |
RYAN, JEFFREY, R.;MARTIN, SAMUEL, K.;SMITHYMAN, ANTHONY, M. |
分类号 |
C07K14/44;G01N33/53;G01N33/569;(IPC1-7):G01N/ |
主分类号 |
C07K14/44 |
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地址 |
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