发明名称 |
CHLOROPHYLL AND BACTERIOCHLOROPHYLL ESTERS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
摘要 |
Novel C-13<2>-COXR1, C-17<2>-COXR2 and C-13<2>-COXR1, C-17<2>-COXR1 derivatives of chlorophyll and bacteriochlorophyll compounds are provided wherein X is O, S or N and R1 and R2 , the same or different, may be an optionally substituted hydrocarbyl , amino acid, peptide, protein or saccharide radical. The compounds are for use in photodynamic therapy (PDT), for diagnosis of tumors, and for killing cells and infectious agents such as bacteria and virus, both in biological products and in living tissues. |
申请公布号 |
WO0140232(A1) |
申请公布日期 |
2001.06.07 |
申请号 |
WO2000IL00811 |
申请日期 |
2000.12.01 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;SCHEER, HUGO;KAMMHUBER, NINA;SCHERZ, AVIGDOR;BRANDIS, ALEXANDER;SALOMON, YORAM |
发明人 |
SCHEER, HUGO;KAMMHUBER, NINA;SCHERZ, AVIGDOR;BRANDIS, ALEXANDER;SALOMON, YORAM |
分类号 |
A61K31/409;A61K31/555;A61K31/7052;A61K41/00;A61K49/00;A61P31/04;A61P31/12;A61P35/00;C07B61/00;C07D487/22;C07H13/04;C07H13/10;C07H15/26;C07K1/20;C07K2/00;(IPC1-7):C07D487/22;C07K14/795;C12P17/18;A61K31/40;A61P33/00 |
主分类号 |
A61K31/409 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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