发明名称 COMMINUTED FORM OF 3-{4-[2-(4-<i>TERT</i>-BUTOXYCARBONYLAMINOPHENYL)ETHOXY]PHENYL}-(S)-2-ETHOXY PROPANOIC
摘要 The present invention relates to a reduced particle size form of the compound 3-{4-[2-(4-&lt;i&gt;tert&lt;/i&gt;-butoxycarbonylaminophenyl)ethoxy]phenyl}-(S)-2-ethoxy propanoic acid, as shown in formula (I), or a pharmaceutically acceptable salt thereof or a solvate of either thereof. The invention also concerns methods of treating one or more conditions associated with Insulin Resistance Syndrome using the reduced particle size form of the compound, or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use in one or more of said conditions. The invention further concerns pharmaceutical compositions containing the reduced particle size form of the compound, or a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient, as well as processes for the manufacture of the reduced particle size form of the compound, or a pharmaceutically acceptable salt thereof.
申请公布号 WO0140166(A1) 申请公布日期 2001.06.07
申请号 WO2000SE02380 申请日期 2000.11.29
申请人 ASTRAZENECA AB;HALLGREN, AGNETA;ROOS, KRISTINA 发明人 HALLGREN, AGNETA;ROOS, KRISTINA
分类号 A61K9/14;A61K31/27;C07C271/28;(IPC1-7):C07C271/28;A61K31/325;A61P3/00;A61P5/48 主分类号 A61K9/14
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