发明名称 Aralkyl-1,2-diamines having calcimimetic activity and preparation mode
摘要 The invention concerns compounds of general formula (I) wherein: X represents a SO2 or CH2 group; R1 represents a hydrogen or halogen atom or an alkoxy, aryl aralkyl group or an alkyl group substituted or not with one or several halogen atoms, n is equal to 0, 1 or 2, and R2 represents a hydrogen or halogen atom or an alkyl or alkoxy group, and their salt with a pharmaceutically acceptable acid. The invention also concerns the method for preparing said compounds, pharmaceutical compositions containing them and their use as modulator of CaSR activity and as medicine particularly designed for treating diseases or physiological disorders involving modulation of CaSR activity.
申请公布号 AU1400801(A) 申请公布日期 2001.06.06
申请号 AU20010014008 申请日期 2000.11.08
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 发明人 MARTIAL RUAT;PIERRE JEAN-PAUL SERGE JACQUES POTIER;ROBERT DODD;PHILIPPE MARCEL DAUBAN;HELENE VERONIQUE FAURE
分类号 A61P1/04;A61K31/132;A61K31/18;A61P3/00;A61P3/14;A61P5/00;A61P5/22;A61P9/10;A61P13/12;A61P19/10;A61P25/28;A61P35/00;C07C211/27;C07C217/08;C07C311/05;C07C311/16;C07C311/18;C07C311/29;C07C311/38;C07D333/34;C07F7/08 主分类号 A61P1/04
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