| 发明名称 |
Heterocyclic sulfamides |
| 摘要 |
The compounds of formula (I)wherein R1, R2 and X have the significance as given in the description, are inhibitors of endothelin receptors and can therefore be used for the treatment of disorders which are associated with abnormal vascular tone and endothelial dysfunction.
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| 申请公布号 |
US6242601(B1) |
申请公布日期 |
2001.06.05 |
| 申请号 |
US20000482810 |
申请日期 |
2000.01.13 |
| 申请人 |
HOFFMAN-LA ROCHE INC. |
发明人 |
BREU VOLKER;COASSOLO PHILIPPE;HUBER ROLF;NEIDHART WERNER;RAMUZ HENRI;ROUX SéBASTIEN;WESSEL HANS PETER |
| 分类号 |
A61K31/505;A61K31/506;A61P1/04;A61P1/16;A61P1/18;A61P3/04;A61P7/02;A61P9/00;A61P9/04;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P15/10;A61P25/06;A61P27/06;A61P35/00;A61P37/02;A61P43/00;C07D213/00;C07D239/00;C07D271/00;C07D277/00;C07D401/12;C07D401/14;C07D405/14;C07D413/14;C07D417/12;C07D417/14;(IPC1-7):C07D239/28 |
主分类号 |
A61K31/505 |
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