| 摘要 |
PURPOSE: A pharmaceutical composition for increasing mitochondria DNA copy number containing S-adenosyl methionine(SAM or AdoMet) is provided, which is useful for prevention and treatment of side effect accompanied by anticancer treatment and insulin-resistance syndrome from diabetes. CONSTITUTION: The pharmaceutical composition for increasing of mitochondria DNA copy number is can be prepared in the form of a medicine for oral(e.g., tablets, capsules), or an injection. The tablet for increasing mitochondria DNA copy numb contains S-adenosyl methionine(SAM or AdoMet) as a main ingredient; and diluents(e.g., lactose, dextrose, sucrose, mannitol, sorbitol, cellulose and/or glycine), lubricants(e.g., silica, talc, stearic acid or its Mg or Ca salt, and/or polyethylene glycol), binding agents(e.g., MgAl silicate, starch paste, gelatin, tragacans, methylcellulose, sodium carboxymethylcellulose and/or pycolidine), and disintegrator(e.g., starch, agar, alginic acid or its Na salt).
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