ILK-2, an integtrin-linked kinase

摘要

The invention concerns a process isolating and characterising an isoform of integrin-linked kinase, called ILK-2, which is overexpressed in cancer cells with high invasive potential. The invention concerns a method for detecting and/or quantifying ILK-2 in a biological sample by RFLP technique. Another aspect of the invention concerns a method for screening compounds capable of inhibiting ILK-2, and the use of said compounds for treating various pathologies, in particular in cancer for avoiding and/or preventing metastases.